abstract：OBJECTIVE:A high protein content of nonhydrolyzed infant formula exceeding metabolic requirements can induce rapid weight gain and obesity. Hydrolyzed formula with too low protein (LP) content may result in inadequate growth. The aim of this study was to investigate noninferiority of partial and extensively hydrolyzed ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ahrens B,Hellmuth C,Haiden N,Olbertz D,Hamelmann E,Vusurovic M,Fleddermann M,Roehle R,Knoll A,Koletzko B,Wahn U,Beyer K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:In 2011, the United States Surgeon General issued a call to action to "identify and address obstacles to greater availability of safe banked donor milk for fragile infants." The purpose of the present study is to analyze patterns in donor human milk (DHM) and fortifier use in level 2, 3, and 4 neonatal facili...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Perrin MT

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Differentiating ulcerative colitis (UC) and Crohn disease (CD) can be clinically challenging, especially in children. Granulomatous inflammation has traditionally been attributed to CD. Crypt-associated giant cells and granulomas, however, have been observed in colonic biopsies of patients with UC. This phen...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Queliza K,Ihekweazu FD,Schady D,Jensen C,Kellermayer R

更新日期：2018-04-01 00:00:00

abstract：:Herpes simplex virus (HSV) is a common cause of infectious esophagitis. The aim of this retrospective study is to identify comorbid and predisposing conditions and sequelae of HSV esophagitis in immunocompetent children. We reviewed 16 cases of HSV esophagitis diagnosed from January 1982 to March 2016. Five patients w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fritz J,Lerner D,Suchi M

更新日期：2018-04-01 00:00:00

abstract：:On the occasion of the 50th anniversary of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), its close partner associations submitted comments and felicitations which are presented here. These include words from the Latin American (LASPGHAN), North American (NASPGHAN) and Panarab...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Golden B,Stiris T,Panés J,Namazova-Baranova L,Van Gossum A,Boeing H,Bhutta ZA,Madrazo A,Heubi JE,Mouane N,Fockens P,Koletzko B

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:On the basis of studies with hepatorenal syndrome, it is widely regarded that renal function is impacted in chronic liver disease (CLD). Therefore, we investigated renal function in children with CLD. METHODS:In a retrospective study of 277 children with CLD, renal function was investigated as glomerular fi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Berg UB,Németh A

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Endoscopic retrograde cholangiopancreatography is used to manage biliary pathology in pediatric patients. Plastic biliary stents have been used in this population for obstructive lesions and bile leaks; however, they are sometimes not effective due to migration, occlusion, or ineffective sealing. Fully cover...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mark JA,Mack CL,Marwan AI,Kramer RE

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Hirschsprung disease (HSCR) has previously been associated with inflammatory bowel disease (IBD). There are no data to show how common this association is. The aim of the present study was to assess the risk of IBD in individuals with HSCR in a population-based cohort. METHODS:This was a nationwide, populat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Löf Granström A,Amin L,Arnell H,Wester T

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not bee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ariff S,Krebs NF,Westcott JE,Hambidge M,Miller LV,Rizvi A,Soofi SB,Bhutta ZA

更新日期：2018-03-01 00:00:00

abstract：:The incidence of inflammatory bowel disease (IBD) is steadily on the rise in Western and in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. Furthermore, nutrition is involved in several aspects ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shaoul R,Brown S,Day AS

更新日期：2018-03-01 00:00:00

abstract：:Paediatric autoimmune liver disease is characterized by inflammatory liver histology, circulating autoantibodies, and increased levels of IgG, in the absence of a known etiology. Three conditions have a likely autoimmune pathogenesis: autoimmune hepatitis (AIH), autoimmune sclerosing cholangitis, and de novo AIH after...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mieli-Vergani G,Vergani D,Baumann U,Czubkowski P,Debray D,Dezsofi A,Fischler B,Gupte G,Hierro L,Indolfi G,Jahnel J,Smets F,Verkade HJ,Hadžić N

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Our previous studies suggested that human milk proteases begin to hydrolyze proteins in the mammary gland and continue within the term infant' stomach. No research has measured milk protease and pepsin activity in the gastric aspirates of preterm infants after human milk feeding. This study investigated how t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Demers-Mathieu V,Nielsen SD,Underwood MA,Borghese R,Dallas DC

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is treated with dietary modification and/or pharmacologic management with swallowed topical steroids. Swallowed fluticasone propionate (FP) and oral viscous budesonide (OVB) have proven to be effective in resolving symptoms and reversing histologic changes in children and adult...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fable JM,Fernandez M,Goodine S,Lerer T,Sayej WN

更新日期：2018-01-01 00:00:00

abstract：:Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated wit...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hall CHT,Nguyen N,Furuta GT,Prager J,Deboer E,Deterding R,Menard-Katcher C,Capocelli KE,Kramer RE,Friedlander JA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Adult-based guidelines support the use of the pull (extraction) endoscopic technique in managing esophageal food bolus impactions (FBIs) but allow the consideration of the push (advancement) technique with caution based on available published literature. The North American Society for Pediatric Gastroenterol...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kriem J,Rahhal R

更新日期：2018-01-01 00:00:00

abstract：:This document provides recommendations developed by the ESPGHAN Working Group on Probiotics and Prebiotics on the role of probiotics in the prevention of nosocomial diarrhea in children based on a systematic review of previously completed systematic reviews and of subsequently published randomized controlled trials. T...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hojsak I,Szajewska H,Canani RB,Guarino A,Indrio F,Kolacek S,Orel R,Shamir R,Vandenplas Y,van Goudoever JB,Weizman Z,ESPGHAN Working Group for Probiotics\/Prebiotics.

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:We conducted this mass screening study to determine the prevalence of celiac disease (CD) and characterize the celiac iceberg among Saudi pediatric population in Riyadh, the capital city of Saudi Arabia. METHODS:During the study period (January 2014-June 2016), we have conducted a cross-sectional, mass scre...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Al-Hussaini A,Troncone R,Khormi M,AlTuraiki M,Alkhamis W,Alrajhi M,Halal T,Fagih M,Alharbi S,Bashir MS,Chentoufi AA

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to use linear programming (LP) analyses to adapt New Complementary Feeding Guidelines (NCFg) designed for infants aged 6 to 12 months living in poor socioeconomic circumstances in Bogota to ensure dietary adequacy for young children aged 12 to 23 months. DESIGN:A secondary data analy...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tharrey M,Olaya GA,Fewtrell M,Ferguson E

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:Data on the outcomes of children with perianal Crohn disease (pCD) are limited, although its presence is often used for justifying early use of biologics. We aimed to assess whether pCD in children is associated with more severe outcomes as found in adults. METHODS:Data were extracted from the ImageKids dat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Assa A,Amitai M,Greer ML,Castro DA,Kuint RC,Martínez-León M,Herman-Sucharska I,Coppenrath E,Anupindi S,Towbin A,Moote D,Konen O,Pratt LT,Griffiths A,Turner D,ImageKids Study Group.

更新日期：2017-09-01 00:00:00

abstract：:As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and th...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： McLin VA,Allen U,Boyer O,Bucuvalas J,Colledan M,Cuturi MC,d'Antiga L,Debray D,Dezsofi A,Goyet JV,Dhawan A,Durmaz O,Falk C,Feng S,Fischler B,Franchi-Abella S,Frauca E,Ganschow R,Gottschalk S,Hadzic N,Hierro L,Hor

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The prevalence of celiac disease (CD) has increased significantly in recent years, and risk prediction and early diagnosis have become imperative especially in at-risk families. In a previous study, we identified individuals with CD based on the expression profile of a set of candidate genes in peripheral blo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Galatola M,Cielo D,Panico C,Stellato P,Malamisura B,Carbone L,Gianfrani C,Troncone R,Greco L,Auricchio R

更新日期：2017-09-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) affects many children and adolescents in terms of their confidence, acceptance, and ability to build friendships. New Zealand held its first summer camp for children with IBD in January 2015. We obtained feedback from the campers (ages 10-18 years) in terms of their confidence, accepta...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： McCombie A,Gearry RB,Lopez RN,Lönnfors S,Day AS

更新日期：2017-09-01 00:00:00

abstract：:Visceral hypersensitivity and abnormal coping are common in children with functional abdominal pain disorders (FAPDs). Thus, it would be expected that children with visceral hypersensitivity would report more pain if their gut is acutely inflamed. The aim of the study was to compare clinical symptoms and somatization ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Saps M,Mintjens S,Pusatcioglu CK,Cohen DM,Sternberg P

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:A growing population of adolescents/young adults with eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE) will need to transition from pediatric to adult health providers. Measuring health care transition (HCT) readiness is critical, but no studies have evaluated this process in EoE/EGE. We...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Eluri S,Book WM,Kodroff E,Strobel MJ,Gebhart JH,Jones PD,Menard-Katcher P,Ferris ME,Dellon ES

更新日期：2017-07-01 00:00:00

abstract：:The current era of healthcare reform emphasizes the provision of effective, safe, equitable, high-quality, and cost-effective care. Within the realm of gastrointestinal endoscopy in adults, renewed efforts are in place to accurately define and measure quality indicators across the spectrum of endoscopic care. In pedia...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kramer RE,Walsh CM,Lerner DG,Fishman DS

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Iron deficiency (ID) in children with inflammatory bowel disease (IBD) is either an absolute (depleted iron stores) or a functional deficiency (caused by chronic inflammation). Differentiating between these 2 types of ID is important because they require a different therapeutic approach. Zinc protoporphyrin ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Akkermans MD,Vreugdenhil M,Hendriks DM,van den Berg A,Schweizer JJ,van Goudoever JB,Brus F

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Beneficial therapeutic effect of probiotics has been reported in children with the irritable bowel syndrome (IBS) but not consistently in other functional abdominal pain-related disorders. The aim of the present study was to investigate the effect of Lactobacillus reuteri DSM 17938 in the treatment of functi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jadrešin O,Hojsak I,Mišak Z,Kekez AJ,Trbojević T,Ivković L,Kolaček S

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Eosinophilic esophagitis (EoE) is a clinicopathologic disorder characterized by infiltration of eosinophils into the esophagus. Primary treatment approaches include topical corticosteroids and/or food elimination. The aim of the present study was to compare the effectiveness of combination therapy (topical c...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Constantine G,Seth N,Chokshi N,Minard CG,Guffey D,Olive AP,Davis CM

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to develop a questionnaire evaluating the frequency of symptoms over time of concomitant childhood bladder and bowel dysfunctions (CBBDs) in 5- to 12-year-old children and to assess its feasibility and aspects of validity and reliability. METHODS:The Childhood Bladder and Bowel Dysf...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van Engelenburg-van Lonkhuyzen ML,Bols EMJ,Bastiaenen CHG,Benninga MA,de Bie RA

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Endoscopy is integral to the diagnosis and management of many gastrointestinal problems in children. Recently the number of endoscopic procedures performed has increased considerably worldwide raising questions about their appropriateness and cost-efficacy. OBJECTIVES:The aim of the study was to determine...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Thomson M,Sharma S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Although perianal complications of Crohn disease (CD) are commonly encountered in clinical practice, the epidemiology of perianal CD among populations of children is poorly understood. We sought to characterize the prevalence of perianal disease in a large and diverse population of pediatric patients with CD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Adler J,Dong S,Eder SJ,Dombkowski KJ,ImproveCareNow Pediatric IBD Learning Health System.

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Although several studies report on the experience with adult eosinophilic esophagitis (EoE)-related stricture, outcomes for pediatric patients with EoE-associated fibrostenosis and stricture is more limited. To address this, we aim to identify the adverse event (AE) rate and short-term outcomes of the larges...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Menard-Katcher C,Furuta GT,Kramer RE

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:For a large portion of youth, pain-associated functional gastrointestinal disorders (FGIDs) are associated with significant impairment over time. Clinically feasible methods to categorize youth with FGIDs at greatest risk for persistent pain-related impairment have not yet been identified. METHODS:Measure...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cunningham NR,Jagpal A,Peugh J,Farrell MK,Cohen MB,Mezoff AG,Lynch-Jordan A,Kashikar-Zuck S

更新日期：2017-05-01 00:00:00

abstract：:We performed a Japanese nationwide survey of pediatric-onset chronic nonspecific multiple ulcers of the small intestine between January 2000 and July 2013 in 176 institutions of pediatric surgery or pediatric gastroenterology and clarified the clinical features associated with genetic abnormalities in the Solute Carri...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Uchida K,Nakajima A,Ushijima K,Ida S,Seki Y,Kakuta F,Abukawa D,Tsukahara H,Maisawa SI,Inoue M,Araki T,Umeno J,Matsumoto T,Taguchi T

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The Pediatric Ulcerative Colitis Activity Index (PUCAI) is a noninvasive clinician-based index, which reflects disease severity in pediatric ulcerative colitis (UC) when no endoscopy is performed. Here, we aimed to explore signs and symptoms important to children with UC and their caregivers as the first sta...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Marcovitch L,Nissan A,Mack D,Otley A,Hussey S,Mclean B,Lewis M,Croft N,Barakat FM,Griffiths AM,Turner D

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Familial intrahepatic cholestasis 1 (FIC1) deficiency is caused by a mutation in the ATP8B1 gene. Partial external biliary diversion (PEBD) is pursued to improve pruritus and arrest disease progression. Our aim is to describe clinical variability after PEBD in FIC1 disease. METHODS:We performed a single-cen...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Squires JE,Celik N,Morris A,Soltys K,Mazariegos G,Shneider B,Squires RH

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Oral viscous budesonide is a recent therapeutic option for eosinophilic oesophagitis (EoE) compared with dietary restriction and inhaled steroids. This single-centre, open-label, not blinded study aims to evaluate the efficacy and safety of a new, preprepared oral viscous budesonide suspension (PVB) in child...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Oliva S,Rossetti D,Papoff P,Tiberti A,Rossi P,Isoldi S,Amil Dias J,Lucarelli S,Cucchiara S

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Infectious diarrhea, a leading cause of morbidity and deaths, is less prevalent in breastfed infants compared with infants fed infant formula. The dominant human milk oligosaccharide (HMO), α-1,2-fucosyllactose (2'-FL), has structural homology to bacterial adhesion sites in the intestine and may in part expl...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cilieborg MS,Sangild PT,Jensen ML,Østergaard MV,Christensen L,Rasmussen SO,Mørbak AL,Jørgensen CB,Bering SB

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:Gastrointestinal (GI) mucositis is an adverse-effect of chemo- and radiotherapy. Oral insulin has been suggested as possible intestinal growth factor and possible intervention for GI mucositis. We aimed to determine the effect of oral insulin on the severity and recovery of mucositis in a methotrexate (MTX)-...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kuiken NS,Rings EH,Havinga R,van der Aa SA,Groen AK,Tissing WJ

更新日期：2017-02-01 00:00:00

abstract：:We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patien...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Schoepfer AM,Vavricka S,Safroneeva E,Fournier N,Manser C,Frei P,Deltenre P,Rogler G,Straumann A,Ezri J,Nydegger A,Braegger C

更新日期：2017-02-01 00:00:00